

In 1987, she appeared in the hit film Inaam Dus Hazaar alongside Sanjay Dutt. Her other releases that year such as Dilwaala (1986) and Allah Rakha were average performers at the box office. That same year she appeared in a romantic drama Dahleez alongside Jackie Shroff and Raj Babbar, which dealt with the taboo topic of infidelity, the film though underperformed at the box office. The film gained immense critical acclaim and many critics said Meenakshi Seshadri has acted in Swati the way Amitabh Bachchan acts in his films. She appeared in many critically acclaimed films in 1986, mainly Swati, a woman-centric art house film, she performed the title role amongst an ensemble cast. In the same year she acted with Rajinikanth in Mahaguru as his heroine. Subhash Ghai again cast her in his next film Meri Jung, alongside Anil Kapoor, which became one of the highest-grossing films of the year. She then appeared in the film Hoshiyar alongside Jeetendra. Some of her films were moderately successful, namely Swati, Mera Jawab and Aandhi Toofan. This resulted in her gaining a major foothold in the industry. The film became one of the highest revenue earning films of the year 1985. Her next film Bewafai, again opposite Rajesh Khanna with Rajinikanth in a negative role.

She then appeared in many commercially unsuccessful films, mainly Love Marriage, Paisa Ye Paisa, and Lover Boy. She then appeared with Rajesh Khanna in Awara Baap in which she had a double role, but the film underperformed.

The film went on to become a blockbuster and Seshadri became an overnight star She, immediately after the success of Hero, got offers to star with Superstar Rajesh Khanna.

She was encouraged by Subhash Ghai who cast her as his leading lady alongside another newcomer Jackie Shroff in Hero. After Painter Babu, Seshadri decided to quit acting. Meenakshi Seshadri, born as Shashikala Seshadri, made her debut in the flop film Painter Babu, a 1983 Telugu/Hindi bilingual film opposite Rajiv Goswami, brother of Manoj Kumar.
